| .AIDS |
|
Acquired immunodeficiency syndrome. A
condition in which the normal immune system becomes depressed,
rendering the affected individual unable to fight a number of
serious and fatal infections. Human T-cell leukemia/lymphoma
virus (HTLV-III) is associated with AIDS. The virus has been
renamed human immunodeficiency virus (HIV). The presence of
HIV antigen in the blood will confirm that an individual is
infected with the virus and has AIDS. The presence of HIV
antibody in the blood confirms that an individual has been
infected with the AIDS virus. .
|
| .Alcohol |
|
Ethanol, ethyl alcohol (depressant). .
|
| .Aliquot |
|
A portion of a specimen used for testing. .
|
| .A-sample |
Test sample
(see also B-sample). |
| .Accuracy |
Closeness
to the true value. |
| .Antibody (Ab) |
|
A
substance produced by the body in response to an antigen that
specifically reacts with the antigen to destroy, inhibit, or
neutralize it. The body produces antibodies as a defense against foreign substances. Antibodies may be identified and
measured to determine whether an individual has been infected
by a pathogen.
.
|
| .Antigen (Ag)
|
|
Any
substance that when introduced into the body (such as the
protein coat of an invading pathogen) causes the formation of
antibodies. Ag is also found on tissue and blood cells, and in
body fluids. Measurement of antigen can help determine whether
a particular disease will become active. .
|
| .Bloodborne |
|
An infectious agent is bloodborne when it is
transmitted from one person to another via blood or blood
products. .
|
| .B-sample |
|
Referee sample (to be refrigerated for one
year in case of a legal challenge). .
|
| .BAC |
|
Blood Alcohol Concentration. .
|
| .BAT |
|
Blood Alcohol Technician. .
|
| .Blind test |
|
A quality control test of a known sample but
unknown to the test performer. .
|
| .Borderline |
|
A screening test result close to the cut-off
value (which shall be read negative). .
|
| .Calibration |
|
Periodic adjustment of a device to a base standard. .
|
| .C-o-c |
|
Chain-of-custody (seals, bags, documents and
procedures). .
|
| .Collection pad |
|
A
specially treated cotton fiber pad that is attached to a nylon
stick. This collection pad draws antibodies from the tissues
of the gum and cheek into the mouth and into the pad. The
collection pad is placed between the lower cheek and gum for a
minimum of 2 minutes.
|
| .Collector |
|
Person supervising sampling and
performing of screening tests. .
|
| .Confirmed |
|
A positive screening test result confirmed
by GC-MS. .
|
| .Confirmation test |
|
Step two, in the two-step testing procedure
(GC-MS technology). .
|
| .Cross reaction |
|
Other similar drugs' interference with the
detection system. .
|
| .Cut-off |
|
Definition of a threshold/level to
discriminate between positive/negative. .
|
| .Deoxyribonucleic acid
(DNA) |
|
The
carrier of genetic information, it is found on chromosomes in
the cell nucleus. It is a complex protein composed of
different subunits that contain nitrogen, a complex sugar,
phosphoric acid, and other constituents arranged in specific
sequences. Genes consist of DNA.
|
| .Donor |
|
Person providing specimens for testing. .
|
| .EAP |
|
Employee Assistance Program. .
|
| .EBT |
|
Evidential Breath Test (device). .
|
| .Ethanol
|
|
Ethyl
alcohol, the type used in alcoholic beverages, medicines, and
food products. Blood levels of ethanol can be ascertained by
tests that indicate the degree of intoxication. Alcohol
affects brain function (central nervous system depressant) and
may produce chronic illness in susceptible
individuals. .
|
| .False negative |
|
A negative test result of a specimen being
positive. .
|
| .False positive |
|
A positive test result of a specimen being
negative. .
|
| .GC-MS |
|
Gas Chromatography & Mass Spectrometry
(confirmation test). .
|
| .Hepatitis
|
|
Inflammation of the liver, usually caused by
bacterial or viral infection, drugs (including alcohol),
toxins, or parasites. This disease is characterized by an
enlarged liver, jaundice, diminished appetite, nausea, and
abdominal pain. There are at least three forms of viral
hepatitis (hepatitis A, hepatitis B, and non-A, non-B
hepatitis). Hepatitis A, also known as infectious hepatitis,
is transmitted by contaminated food or water and personal
contact, and is most often found in children or young adults.
Hepatitis B, formerly called serum hepatitis, may be
transmitted through contaminated blood or needles, as well as
sexually, and has a longer incubation period than that of
hepatitis A. Hepatitis B can result in chronic active
hepatitis. Non-A, non-B hepatitis is also transmitted through
blood and can cause severe liver damage. Radioimmunoassays and
enzyme-linked immunosorbent assays may be used to screen for
hepatitis. .
|
| .Hepatitis B surface
antigen (HBsAG) |
|
A part
of the hepatitis B virus that, when in the blood, is one of
the earliest markers of infection with hepatitis B virus,
appearing even before symptoms. Also found in blood of a
carrier. HBsAG is tested for in the differential diagnosis of
hepatitis. .
|
| .Initial test |
|
Screening test. .
|
| .Immunoassay |
|
Identification of a target drug through its
capability to act as an antigen. .
|
| .MRO |
|
Medical Review Officer. .
|
| .NIDT |
|
Non-Instrumented Drug Test (device). .
|
| .Non-negative |
|
Preliminary positive. .
|
| .Oral Fluid - Oral
mucosal transudate (OMT) |
|
An
oral fluid that can be obtained from the tissues of the cheek
and gum. OMT is distinct from saliva which contains a lower
amount of suitable antibodies to accurately test for HIV and
other infections. OMT has relatively high concentrations of
serum derived antibodies, immunoglobulin G (IgG) antibodies,
and overcomes the contaminants found in saliva (eg, bacteria).
A sample of antibody-rich OMT can be collected and used to
accurately test for the presence of many infectious diseases.
.
|
| .OTC |
|
Over the counter drugs (no prescription). .
|
| .Precision |
|
Ability to reach the same test result/value
when reproducing the test. .
|
| .Preliminary positive |
|
A preliminary positive screening test result
- to be confirmed by GC-MS. .
|
| .Saliva
|
|
A clear, tasteless, odourless, slightly
alkaline fluid secreted into the mouth by the salivary glands.
.
|
| .Screening test |
|
Step one in the two-step testing procedure
(immunoassay). .
|
| .Sensitivity |
|
The smallest concentration of a drug
(metabolite) that can be detected. .
|
| .Serum |
|
The
clear, yellowish fluid obtained upon separating whole blood
into its solid and liquid components. Also called blood serum.
.
|
| .Sexually transmitted
disease (STD) |
|
A
disease caused by a microorganism that is passed to another
person during sexual contact.
|
| .Specificity |
|
Ability to discriminate between various,
similar drugs. .
|
| .Specimen
|
|
A
sample, as of tissue, blood, oral fluid, saliva, urine etc. used for analysis and
diagnosis. .
|
| .Specimen vial |
|
A
small plastic container for liquid specimens.
|
| .Split samples |
|
Practice
of splitting the primary sample in two (A & B samples).
|
| .To be confirmed |
|
A
non-negative screening test result to be confirmed by GC-MS.
|
| .True negative |
|
A
negative test result of a specimen being negative.
|
| .True positive |
|
A
positive test result of a specimen being positive.
|
| .Unconfirmed |
|
A
preliminary positive screening test result proven negative by
GC-MS.
|