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DRUGS

Alcohol
Nicotine
Drugs of Abuse
Drugs in Sport

 
SPECIMENS

Blood
Oral Fluid
Saliva
Urine
Sweat
Hair
DETECTION

Marijuana
Opiates
Amphetamine
Methamphetamine
Benzodiazepines
Cocaine
TESTING

Screening
Confirmation
On-site
Laboratory
COMPARISON

Urine vs.
Oral Fluid
GLOSSARY
STUDIES


Glossary
.AIDS 


Acquired immunodeficiency syndrome. A condition in which the normal immune system becomes depressed, rendering the affected individual unable to fight a number of serious and fatal infections. Human T-cell leukemia/lymphoma virus (HTLV-III) is associated with AIDS. The virus has been renamed human immunodeficiency virus (HIV). The presence of HIV antigen in the blood will confirm that an individual is infected with the virus and has AIDS. The presence of HIV antibody in the blood confirms that an individual has been infected with the AIDS virus.
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.Alcohol 


Ethanol, ethyl alcohol (depressant).
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.Aliquot 


A portion of a specimen used for testing.
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.A-sample 

Test sample (see also B-sample).
.Accuracy

Closeness to the true value.
.Antibody (Ab)


A substance produced by the body in response to an antigen that specifically reacts with the antigen to destroy, inhibit, or neutralize it. The body produces antibodies as a defense against foreign substances. Antibodies may be identified and measured to determine whether an individual has been infected by a pathogen.
 
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.Antigen (Ag)


Any substance that when introduced into the body (such as the protein coat of an invading pathogen) causes the formation of antibodies. Ag is also found on tissue and blood cells, and in body fluids. Measurement of antigen can help determine whether a particular disease will become active.

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.Bloodborne


An infectious agent is bloodborne when it is transmitted from one person to another via blood or blood products.

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.B-sample


Referee sample (to be refrigerated for one year in case of a legal challenge).

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.BAC


Blood Alcohol Concentration.

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.BAT


Blood Alcohol Technician.

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.Blind test


A quality control test of a known sample but unknown to the test performer.

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.Borderline


A screening test result close to the cut-off value (which shall be read negative).

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.Calibration


Periodic adjustment of a device to a base standard.

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.C-o-c


Chain-of-custody (seals, bags, documents and procedures).

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.Collection pad


A specially treated cotton fiber pad that is attached to a nylon stick. This collection pad draws antibodies from the tissues of the gum and cheek into the mouth and into the pad. The collection pad is placed between the lower cheek and gum for a minimum of 2 minutes.

.Collector


Person supervising sampling and performing of screening tests.

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.Confirmed


A positive screening test result confirmed by GC-MS.

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.Confirmation test


Step two, in the two-step testing procedure (GC-MS technology).

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.Cross reaction


Other similar drugs' interference with the detection system.

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.Cut-off


Definition of a threshold/level to discriminate between positive/negative.

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.Deoxyribonucleic acid (DNA)


The carrier of genetic information, it is found on chromosomes in the cell nucleus. It is a complex protein composed of different subunits that contain nitrogen, a complex sugar, phosphoric acid, and other constituents arranged in specific sequences. Genes consist of DNA.

.Donor


Person providing specimens for testing.

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.EAP


Employee Assistance Program.

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.EBT


Evidential Breath Test (device).

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.Ethanol


Ethyl alcohol, the type used in alcoholic beverages, medicines, and food products. Blood levels of ethanol can be ascertained by tests that indicate the degree of intoxication. Alcohol affects brain function (central nervous system depressant) and may produce chronic illness in susceptible individuals.
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.False negative


A negative test result of a specimen being positive.

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.False positive


A positive test result of a specimen being negative.

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.GC-MS 


Gas Chromatography & Mass Spectrometry (confirmation test).

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.Hepatitis


Inflammation of the liver, usually caused by bacterial or viral infection, drugs (including alcohol), toxins, or parasites. This disease is characterized by an enlarged liver, jaundice, diminished appetite, nausea, and abdominal pain. There are at least three forms of viral hepatitis (hepatitis A, hepatitis B, and non-A, non-B hepatitis). Hepatitis A, also known as infectious hepatitis, is transmitted by contaminated food or water and personal contact, and is most often found in children or young adults. Hepatitis B, formerly called serum hepatitis, may be transmitted through contaminated blood or needles, as well as sexually, and has a longer incubation period than that of hepatitis A. Hepatitis B can result in chronic active hepatitis. Non-A, non-B hepatitis is also transmitted through blood and can cause severe liver damage. Radioimmunoassays and enzyme-linked immunosorbent assays may be used to screen for hepatitis.

.Hepatitis B surface antigen (HBsAG)


A part of the hepatitis B virus that, when in the blood, is one of the earliest markers of infection with hepatitis B virus, appearing even before symptoms. Also found in blood of a carrier. HBsAG is tested for in the differential diagnosis of hepatitis.

.Initial test 


Screening test.

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.Immunoassay 


Identification of a target drug through its capability to act as an antigen.

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.MRO 


Medical Review Officer.

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.NIDT 


Non-Instrumented Drug Test (device).

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.Non-negative 


Preliminary positive.

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.Oral Fluid - Oral mucosal transudate (OMT)


An oral fluid that can be obtained from the tissues of the cheek and gum. OMT is distinct from saliva which contains a lower amount of suitable antibodies to accurately test for HIV and other infections. OMT has relatively high concentrations of serum derived antibodies, immunoglobulin G (IgG) antibodies, and overcomes the contaminants found in saliva (eg, bacteria). A sample of antibody-rich OMT can be collected and used to accurately test for the presence of many infectious diseases.

.OTC 


Over the counter drugs (no prescription).

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.Precision 


Ability to reach the same test result/value when reproducing the test.

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.Preliminary positive 


A preliminary positive screening test result - to be confirmed by GC-MS.

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.Saliva


A clear, tasteless, odourless, slightly alkaline fluid secreted into the mouth by the salivary glands.

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.Screening test 


Step one in the two-step testing procedure (immunoassay).

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.Sensitivity 


The smallest concentration of a drug (metabolite) that can be detected.

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.Serum


The clear, yellowish fluid obtained upon separating whole blood into its solid and liquid components. Also called blood serum.

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.Sexually transmitted disease (STD)


A disease caused by a microorganism that is passed to another person during sexual contact.

.Specificity 


Ability to discriminate between various, similar drugs.

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.Specimen


A sample, as of tissue, blood, oral fluid, saliva, urine etc. used for analysis and diagnosis.
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.Specimen vial


A small plastic container for liquid specimens.

.Split samples


Practice of splitting the primary sample in two (A & B samples).

.To be confirmed


A non-negative screening test result to be confirmed by GC-MS.

.True negative


A negative test result of a specimen being negative.

.True positive


A positive test result of a specimen being positive.

.Unconfirmed


A preliminary positive screening test result proven negative by GC-MS.
 

 

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Drug Testing Pacific

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